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Autoimmune Diseases, Dermatomyositis, Research

Aseptic Meningitis and Intravenous Immunoglobulin (IVIG) Therapy

By Nicole Shine

I’ve written earlier about the massive migraines my husband experiences that have resulted in regular trips to the ER. Before he contracted dermatomyositis, he never had headaches, much less migraines, so we knew it was related to the disease.

Well, not quite. Turns out, the twice-monthly IVIG therapy is behind the migraines. When we visited Johns Hopkins last week, the doctor confirmed that IVIG can cause massive headaches, what he termed aseptic meningitis. There, they spread IVIG treatment across five days, rather than two, to reduce the likelihood of aseptic meningitis. As a side note, the doctor said they don’t recommend continuing IVIG for more than six months when patients are showing improvement.

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